Description

15-Ketoprostaglandin B1 is a specialized prostaglandin analog and a key metabolite of prostaglandin B1, serving as a valuable biochemical tool and reference standard. This compound is crucial for researchers investigating eicosanoid metabolism, oxidative stress pathways, and lipid mediator biology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and analytical laboratories focused on prostaglandin-related studies and method development.

Application

• Biochemical Research: Used as a reference standard and analytical tool in studies of prostaglandin metabolism and eicosanoid signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or metabolite in the research and development of novel anti-inflammatory or lipid-targeting therapeutics.
• Analytical Chemistry: Employed as a high-purity standard for method validation in chromatographic techniques like HPLC and LC-MS for prostaglandin analysis.
• Metabolomics Studies: Acts as a specific biomarker or reference compound in lipidomic profiling to understand oxidative stress and related disease states.
• Enzyme Activity Assays: Utilized as a substrate or product in assays for enzymes involved in prostaglandin synthesis and degradation, such as dehydrogenases.

Basic Information

Product Name	15-Ketoprostaglandin B1
CAS No.	57400-40-5
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	15-Keto PGB1; 15-Oxoprostaglandin B1; 9,15-Dioxoprosta-5,13-dien-1-oic acid; 15-Keto-PGB1; Prostaglandin B1, 15-keto-; 15-Ketoprosta-5,13-dien-1-oic acid, 9,15-dioxo-; 15-Keto PGB1 metabolite
EINECS	Contact for details

Quality Control

Our 15-Ketoprostaglandin B1 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.