Description

Pregnane-3,20-Dione, 17-[(Trimethylsilyl)Oxy]-, Bis(o-Methyloxime), (5 Beta)- is a high-purity, steroidal derivative specifically designed for advanced research and pharmaceutical development. This compound serves as a critical protected intermediate or analytical reference standard in the synthesis of complex steroid hormones and their metabolites. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require precise and reliable building blocks for drug discovery, metabolic studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of bioactive steroid analogs and hormone-based therapeutics.
• Analytical Reference Standard: Used for method development, validation, and quality control in HPLC, LC-MS, and GC-MS analyses within regulatory and research laboratories.
• Metabolic Pathway Research: Employed in studies investigating steroid metabolism, enzyme function, and biochemical pathways.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for the construction of novel steroidal frameworks with potential pharmacological activity.
• Biochemical Reagent: Acts as a substrate or inhibitor in enzymatic assays and receptor binding studies related to steroid hormones.

Basic Information

Product Name	Pregnane-3,20-Dione, 17-[(Trimethylsilyl)Oxy]-, Bis(o-Methyloxime), (5 Beta)-
CAS No.	57305-29-0
Molecular Formula	C26H44N2O3Si
Molecular Weight	460.73 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17-(trimethylsilyloxy)-, bis(O-methyloxime); 17β-(Trimethylsilyloxy)-5β-pregnane-3,20-dione dioxime O-methyl ether; 5β-Pregnan-17α-ol-3,20-dione 17-trimethylsilyl ether bis-O-methyloxime; (5β)-17-[(Trimethylsilyl)oxy]pregnane-3,20-dione bis(O-methyloxime); 57305-29-0; Pregnane derivative TMS-oxime
EINECS	Contact for details

Quality Control

Our Pregnane-3,20-Dione, 17-[(Trimethylsilyl)Oxy]-, Bis(o-Methyloxime), (5 Beta)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool environment. This product is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.