Description

n-(1-Phenylethyl)Sulfamoyl Chloride is a specialized sulfamoyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing sulfonamide and sulfamate functional groups, which are critical pharmacophores in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate sulfonamide moieties for enhanced bioactivity.
• Chemical Research & Development: Serves as a versatile electrophile in academic and industrial R&D for exploring new synthetic pathways and creating complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional polymers where the introduction of a sulfamoyl group is required.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	n-(1-Phenylethyl)Sulfamoyl Chloride
CAS No.	57053-73-3
Molecular Formula	C8H10ClNO2S
Molecular Weight	219.69 g/mol
Synonyms	N-(1-Phenylethyl)sulfamoyl chloride; (1-Phenylethyl)sulfamoyl chloride; α-Methylbenzenemethanesulfonamide chloride; N-(α-Methylbenzyl)sulfamoyl chloride; 1-Phenylethylsulfamoyl chloride; Benzenemethanesulfonamide, N-(1-phenylethyl)-, chloride; Sulfamoyl chloride, N-(1-phenylethyl)-
EINECS	Contact for details

Quality Control

Our n-(1-Phenylethyl)Sulfamoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.