Description

(-)-n-Demethyl Deprenyl is a high-purity, enantiomerically pure chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters as a key chiral building block for the development of novel active pharmaceutical ingredients (APIs) and research compounds targeting neurological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules and novel therapeutic agents.
• Neurological Research: Used as a reference standard and building block in the study of monoamine oxidase (MAO) inhibitors and related neurological mechanisms.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Development: Employed in the research and process development stages for creating potential Active Pharmaceutical Ingredients targeting CNS disorders.
• Biochemical Research: Utilized in enzymatic studies and as a tool compound for investigating specific biochemical pathways.
• Contract Synthesis: Supplied to CROs and CMOs for custom synthesis projects requiring high-purity, enantiomerically defined intermediates.

Basic Information

Product Name	(-)-n-Demethyl Deprenyl
CAS No.	56862-28-3
Molecular Formula	C12H17N
Molecular Weight	175.27 g/mol
Synonyms	(R)-(-)-N-Desmethyldeprenyl; (R)-N-Desmethylselegiline; (R)-(-)-N-Desmethyl-Deprenyl; (R)-(-)-Desmethyldeprenyl; (R)-N-Desmethyl-Deprenyl; (R)-(-)-N-Desmethyl Deprenyl; (2R)-1-Phenyl-N-(prop-2-yn-1-yl)propan-2-amine; (-)-Desmethylselegiline
EINECS	Contact for details

Quality Control

Our (-)-n-Demethyl Deprenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent industry standards for research and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.