Description

2-o-[6-Deoxy-2-O,3-O,4-o-Tris(Trimethylsilyl)-α-L-Mannopyranosyl]-3-O,4-O,5-O,6-o-Tetrakis(Trimethylsilyl)-D-Glucose is a highly derivatized, fully protected carbohydrate intermediate, specifically a disaccharide where both glucose and mannose units are extensively silylated. This compound is of critical importance in synthetic organic chemistry as a key protected building block for the precise construction of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced glycochemistry, glycomics research, and the development of novel therapeutics where controlled glycosylation is essential.

Application

• Advanced Oligosaccharide Synthesis: Serves as a crucial, fully protected donor or acceptor molecule in stereoselective glycosylation reactions for constructing complex carbohydrate chains.
• Glycoconjugate Development: Used in the research and production of glycoproteins, glycolipids, and other bioactive conjugates for pharmaceutical applications.
• Glycomics and Chemical Biology: Acts as a standardized intermediate or probe in studies exploring carbohydrate-protein interactions and biological signaling pathways.
• Pharmaceutical Intermediate: A key starting material in the multi-step synthesis of potential drug candidates targeting infections, cancer, or inflammatory diseases.
• Standards and Reference Materials: Provides a high-purity, well-characterized standard for analytical method development and quality control in carbohydrate chemistry.
• Specialty Chemical Research: Employed in academic and industrial R&D for developing new synthetic methodologies and protecting group strategies in carbohydrate chemistry.

Basic Information

Product Name	2-o-[6-Deoxy-2-O,3-O,4-o-Tris(Trimethylsilyl)-α-L-Mannopyranosyl]-3-O,4-O,5-O,6-o-Tetrakis(Trimethylsilyl)-D-Glucose
CAS No.	56784-14-6
Molecular Formula	C39H90O11Si7
Molecular Weight	959.86 g/mol
Synonyms	2-O-(6-Deoxy-2,3,4-tri-O-trimethylsilyl-α-L-mannopyranosyl)-3,4,5,6-tetra-O-trimethylsilyl-D-glucose; D-Glucose, 2-O-[6-deoxy-2,3,4-tri-O-(trimethylsilyl)-α-L-mannopyranosyl]-3,4,5,6-tetra-O-(trimethylsilyl)-; Fully Silylated Glc-Man Disaccharide; Heptakis(trimethylsilyl) Glc-Man Disaccharide Derivative; Protected Trehalose-type Disaccharide; TMS-protected α-D-Glcp-(1→2)-α-L-6dManp
EINECS	Contact for details

Quality Control

Our high-purity carbohydrate intermediates are manufactured under controlled conditions and undergo rigorous analytical characterization. Each batch is verified using advanced techniques including NMR (¹H, ¹³C), HPLC, and Mass Spectrometry to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent hydrolysis of the silyl protecting groups. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.