Description

Karwinskia Toxin T-544 is a specific, naturally occurring phytotoxin isolated from plants of the genus *Karwinskia*. This compound is of significant interest in biochemical and pharmacological research due to its potent biological activity and role as a model toxin for studying neurodegenerative mechanisms. It serves as a critical reference standard and active agent for researchers and developers in the life sciences. Primary demand comes from academic institutions, pharmaceutical R&D laboratories, and diagnostic manufacturers focused on neurotoxicology, plant toxicology, and the development of analytical methods or therapeutic countermeasures.

Application

• Biomedical Research Standard: Used as a high-purity reference compound in studies investigating the etiology and pathology of specific neurodegenerative conditions.
• Pharmacological Studies: Employed in vitro and in vivo to elucidate mechanisms of action, dose-response relationships, and cellular toxicity pathways.
• Diagnostic Development: Serves as a key antigen or calibrator in the development of immunoassays and other diagnostic tests for toxin detection.
• Toxicology & Safety Assessment: Applied in toxicological screening to understand environmental and human health risks associated with *Karwinskia* species exposure.
• Phytochemistry & Natural Products Research: Used for the chemical fingerprinting and metabolic profiling of toxic plants.
• Academic Teaching: A valuable tool for advanced university courses in toxicology, pharmacology, and natural product chemistry.

Basic Information

Product Name	Karwinskia Toxin T-544
CAS No.	56678-09-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	T-544 Toxin; Toxin T544; Karwinskia Toxin; Karwinskia humboldtiana Toxin T-544; (7R,8S)-7-(3,4-Dimethoxyphenyl)-8-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6a,12b-dihydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[2,1-b]isoquinolin-12-ium; Isoquinolinium alkaloid from Karwinskia
EINECS	Contact for details

Quality Control

Every batch of Karwinskia Toxin T-544 is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from analytical techniques such as HPLC, MS, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing desiccated at lower temperatures (-20°C).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.