Description

1,3,6,8-Tetrafluoro-2,7-Naphthyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique electronic properties imparted by the strategic fluorine substitution on the naphthyridine scaffold, making it a critical precursor for developing novel functional materials and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Electronic Materials: Employed in the development of organic semiconductors, light-emitting diodes (OLEDs), and other fluorinated electronic materials due to its electron-deficient character.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and other fluorochemical reactions in academic and industrial R&D settings.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized fluorinated dyes and pigments with unique optical properties.

Basic Information

Product Name	1,3,6,8-Tetrafluoro-2,7-Naphthyridine
CAS No.	56595-13-2
Molecular Formula	C8H2F4N2
Molecular Weight	202.11 g/mol
Synonyms	2,7-Naphthyridine, 1,3,6,8-tetrafluoro-; 1,3,6,8-Tetrafluoronaphthyridine; Tetrafluoronaphthyridine; 1,3,6,8-Tetrafluoro-2,7-diazanaphthalene; 1,3,6,8-Tetrafluoro-2,7-naphthyridine; 56595-13-2; NSC 405124
EINECS	Contact for details

Quality Control

Our 1,3,6,8-Tetrafluoro-2,7-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.