Description

1-Phenyl-1,2,2,2-Tetrafluoroethane, also known as (1,2,2,2-Tetrafluoroethyl)benzene, is a high-value fluorinated aromatic compound. This specialty chemical serves as a critical building block and intermediate in advanced synthesis, offering unique reactivity due to its phenyl and tetrafluoroethyl groups. It is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated motifs for enhanced properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic structures to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Serves as a key precursor for developing advanced herbicides, fungicides, and insecticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a fluorinated core component in the production of high-performance electronic display materials and organic light-emitting diodes (OLEDs).
• Specialty Polymer & Resin Modifier: Incorporated to enhance the chemical resistance, thermal stability, and surface properties of advanced polymers and coatings.
• Organic Synthesis & Catalysis Research: A valuable reagent in academic and industrial R&D for studying fluorination reactions and developing new catalytic methodologies.
• Refrigerant & Propellant Formulation: Investigated for use in next-generation, low-global-warming-potential (GWP) refrigerant blends and specialty aerosol propellants.

Basic Information

Product Name	1-Phenyl-1,2,2,2-Tetrafluoroethane
CAS No.	56424-23-8
Molecular Formula	C8H6F4
Molecular Weight	178.13 g/mol
Synonyms	(1,2,2,2-Tetrafluoroethyl)benzene; α,α,α-Trifluorotoluene, 2,2,2-trifluoro-1-phenylethane; Benzylidyne trifluoride, tetrafluoroethylated; Phenyltetrafluoroethane; 1-Phenyl-1,1,2,2-tetrafluoroethane (common alternate numbering); F4EB; Tetrafluoroethylbenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Phenyl-1,2,2,2-Tetrafluoroethane (CAS 56424-23-8) is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure product integrity and traceability for your critical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids/organic solvents and fluorides/strong alkalis. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/mL
Refractive Index (n20D)	~1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.