Description

Ethyl 3,3,3-Trifluoro-2-Methylpropanoate is a high-purity fluorinated ester building block, essential for introducing the trifluoromethyl group into complex molecular architectures. Its value lies in its role as a versatile synthon for the synthesis of advanced pharmaceuticals, agrochemicals, and specialty materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries.

Application

• Pharmaceutical Intermediate: A key fluorinated building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a critical starting material for synthesizing fluorinated components in electronic display and lighting technologies.
• Polymer & Coating Modifier: Imparts desirable properties such as oil repellency, chemical resistance, and low surface energy to specialty polymers and surface coatings.
• Organic Synthesis Reagent: Employed in various fluorination reactions, Claisen condensations, and as a precursor for other trifluoromethyl-containing acids and ketones.

Basic Information

Product Name	Ethyl 3,3,3-Trifluoro-2-Methylpropanoate
CAS No.	56354-75-7
Molecular Formula	C7H9F3O2
Molecular Weight	170.14 g/mol
Synonyms	Ethyl 3,3,3-Trifluoro-2-Methylpropionate; 2-Methyl-3,3,3-trifluoropropionic Acid Ethyl Ester; 3,3,3-Trifluoro-2-Methylpropionic Acid Ethyl Ester; Ethyl α-Methyl-3,3,3-trifluoropropionate; Ethyl 2-Methyl-3,3,3-trifluoropropanoate; TFMPE; 56354-75-7
EINECS	Contact for details

Quality Control

Our Ethyl 3,3,3-Trifluoro-2-Methylpropanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and HPLC, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.