Description

2,2,2-Trifluoroethylphenylsulfone is a specialized organofluorine compound featuring a sulfone linkage between a phenyl ring and a trifluoroethyl group. This structure makes it a valuable intermediate and building block in advanced chemical synthesis, particularly where the introduction of fluorine atoms is desired to alter the physical, chemical, and biological properties of target molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoroethylsulfone moiety can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, or advanced materials that benefit from the unique properties imparted by fluorine atoms.
• Organic Synthesis Reagent: Employed in various fluorination reactions and as a versatile intermediate in constructing complex molecular architectures for research purposes.
• Ligand and Catalyst Development: Potential use in the design of novel ligands or organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,2,2-Trifluoroethylphenylsulfone
CAS No.	56354-44-0
Molecular Formula	C8H7F3O2S
Molecular Weight	224.20 g/mol
Synonyms	Phenyl 2,2,2-trifluoroethyl sulfone; 2,2,2-Trifluoroethyl Phenyl Sulfone; 1,1,1-Trifluoro-2-(phenylsulfonyl)ethane; α,α,α-Trifluoroethyl Phenyl Sulfone; (2,2,2-Trifluoroethyl)(phenyl)sulfone; Benzenesulfonic acid, 2,2,2-trifluoroethyl ester; 56354-44-0
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroethylphenylsulfone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.