Description

Cyclohexanamine, 3-(Trifluoromethyl)- is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the cyclohexylamine scaffold with a strategically positioned trifluoromethyl group, offering enhanced lipophilicity and metabolic stability to target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the CF₃ group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Material Science Research: Incorporated into specialty polymers and advanced materials to modify surface properties and chemical resistance.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	Cyclohexanamine, 3-(Trifluoromethyl)-
CAS No.	56287-83-3
Molecular Formula	C₇H₁₂F₃N
Molecular Weight	167.17 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexanamine; 3-(Trifluoromethyl)cyclohexylamine; 3-Trifluoromethylcyclohexylamine; (3-Trifluoromethylcyclohexyl)amine; 1-Amino-3-(trifluoromethyl)cyclohexane; 3-Cyclohexylamine, trifluoromethyl-; 3-Trifluoromethyl-1-cyclohexanamine
EINECS	Contact for details

Quality Control

Our production of Cyclohexanamine, 3-(Trifluoromethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.