Description

3-Hydroxybenzenesulfonyl Chloride is a versatile aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its reactive sulfonyl chloride group enables the efficient introduction of sulfonamide or sulfonate functionalities, making it indispensable for creating complex molecular architectures. This intermediate is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, antibiotics, and protease inhibitors.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that require a benzenesulfonyl moiety.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing sulfonated azo dyes and other colorants with enhanced solubility and fastness properties.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, such as sulfonated polyethersulfones for membrane applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new sulfonation reactions and creating novel chemical entities.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and catalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	3-Hydroxybenzenesulfonyl Chloride
CAS No.	56157-93-8
Molecular Formula	C6H5ClO3S
Molecular Weight	192.62 g/mol
Synonyms	m-Hydroxybenzenesulfonyl Chloride; 3-Hydroxybenzene-1-sulfonyl Chloride; 3-Hydroxyphenylsulfonyl Chloride; m-Hydroxyphenylsulfonyl Chloride; 1-Hydroxy-3-sulfonylchloridobenzene; Benzenesulfonyl Chloride, 3-hydroxy-; 3-Hydroxybenzenesulphonyl Chloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxybenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, appearance, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.