Description

5'-Adenylic Acid Pentakis(Trimethylsilyl)Deriv. is a key silylated derivative of adenosine monophosphate, primarily used as a protected intermediate in sophisticated organic synthesis. This compound matters for its role in facilitating complex nucleotide chemistry, enabling precise modifications while protecting reactive functional groups. It is needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, prodrugs, and advanced biochemical research tools.

Application

• Nucleoside and Nucleotide Chemistry: Serves as a crucial protected intermediate for the synthesis of modified nucleosides and nucleotides.
• Pharmaceutical Research: Used in the development and scale-up of antiviral and anticancer nucleoside analog prodrugs.
• Bioconjugation: Acts as a precursor for labeling and cross-linking agents in biochemical assays and diagnostic probe development.
• Process Chemistry: Employed in multi-step synthetic routes where temporary protection of phosphate and hydroxyl groups is required.
• Academic Research: A valuable reagent for studying enzyme mechanisms and metabolic pathways involving adenosine derivatives.
• Material Science: Potential use in creating functionalized surfaces or polymers with nucleotide-based recognition elements.

Basic Information

Product Name	5'-Adenylic Acid Pentakis(Trimethylsilyl)Deriv.
CAS No.	56145-14-3
Molecular Formula	C23H49N5O7Si5
Molecular Weight	668.11 g/mol
Synonyms	Adenosine 5'-monophosphate pentakis(trimethylsilyl) derivative; 5'-AMP pentakis(TMS); TMS-AMP; Pentakis(trimethylsilyl) adenosine-5'-phosphate; Adenosine-5'-monophosphoric acid pentakis(trimethylsilyl) ester; 5'-O-Phosphonoadenosine pentakis(trimethylsilyl) derivative; AMP(TMS)5; 56145-14-3
EINECS	Contact for details

Quality Control

Our 5'-Adenylic Acid Pentakis(Trimethylsilyl)Deriv. is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.