Description

(4-Cyanophenyl)Methanesulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling it to act as a versatile electrophile for introducing the methanesulfonyl (mesyl) moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drugs, including kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that require the sulfonyl group for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and functional materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.
• Peptide Modification: Utilized for the selective sulfonylation of amino acid side chains in peptide chemistry.

Basic Information

Product Name	(4-Cyanophenyl)Methanesulfonyl Chloride
CAS No.	56105-99-8
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	4-Cyanobenzenemethanesulfonyl chloride; p-Cyanophenyl methanesulfonyl chloride; 1-Cyano-4-(chlorosulfonylmethyl)benzene; (4-Cyanobenzyl)sulfonyl chloride; Methanesulfonyl chloride, (4-cyanophenyl)-; Mesyl chloride, 4-cyanophenyl-; 56105-99-8
EINECS	Contact for details

Quality Control

Our (4-Cyanophenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.