Description

2-Ethoxy-5-Fluoropyrimidin-4-Amine is a high-purity fluorinated pyrimidine derivative, a key building block in modern organic synthesis. Its molecular structure makes it a critical intermediate for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of novel nucleoside analogs and other fluorinated drug candidates targeting viral and oncological diseases.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides where the fluoropyrimidine core contributes to biological activity and metabolic stability.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct more complex heterocyclic systems.
• Material Science Applications: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and methodology development.

Basic Information

Product Name	2-Ethoxy-5-Fluoropyrimidin-4-Amine
CAS No.	56076-21-2
Molecular Formula	C6H8FN3O
Molecular Weight	157.15 g/mol
Synonyms	5-Fluoro-2-ethoxypyrimidin-4-amine; 4-Amino-5-fluoro-2-ethoxypyrimidine; 2-Ethoxy-5-fluoropyrimidin-4-ylamine; 5-Fluoro-4-amino-2-ethoxypyrimidine; 56076-21-2; 4-Pyrimidinamine, 5-fluoro-2-ethoxy-; 2-Ethoxy-5-fluoropyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-5-Fluoropyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.