Description

5-Fluoro-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidineacetic Acid is a high-purity fluorinated pyrimidine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for nucleoside and nucleotide analog synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Research: Used in developing novel herbicides and pesticides that leverage the fluoropyrimidine moiety for enhanced bioactivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in custom synthesis and process development.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibitors and metabolic pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials with specific electronic properties.

Basic Information

Product Name	5-Fluoro-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidineacetic Acid
CAS No.	56059-30-4
Molecular Formula	C6H5FN2O4
Molecular Weight	188.11 g/mol
Synonyms	5-Fluoroorotic acid; 5-Fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidineacetic acid; 5-Fluoroorotate; 5-Fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-6-acetic acid; 5-Fluorodihydroorotic acid; 6-Carboxymethyl-5-fluorouracil; 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-acetic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidineacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.