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(13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-8(12),13-Dien-1-Oic Acid Trimethylsilyl Ester CAS NO 56009-45-1


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CAS No.:56009-45-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-8(12),13-Dien-1-Oic Acid Trimethylsilyl Ester is a sophisticated synthetic prostaglandin derivative, specifically designed as a key protected intermediate in advanced pharmaceutical synthesis. Its core value lies in enabling the precise construction of complex bioactive molecules, offering researchers and manufacturers a reliable building block for developing novel therapeutics. This high-purity compound is essential for R&D and production teams in the pharmaceutical and fine chemical industries, particularly those focused on prostaglandin analogs and related lipid mediators.

Application

  • Pharmaceutical Intermediate: A critical protected synthon for the synthesis of prostaglandin analogs and related therapeutic agents.
  • Research & Development: Used in medicinal chemistry programs to explore new drug candidates targeting inflammation, cardiovascular function, and other physiological pathways.
  • Fine Chemical Synthesis: Serves as a specialized building block in multi-step organic syntheses requiring high stereochemical and functional group control.
  • Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of prostaglandin-based pharmaceuticals.
  • Biochemical Research: Utilized in studies investigating the structure-activity relationships (SAR) of eicosanoids and their receptor interactions.

Basic Information

Product Name (13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-8(12),13-Dien-1-Oic Acid Trimethylsilyl Ester
CAS No. 56009-45-1
Molecular Formula C29H53NO4Si2
Molecular Weight 539.91 g/mol
Synonyms 9-(Ethoxyimino)-15-(trimethylsiloxy)prosta-8(12),13-dien-1-oic acid trimethylsilyl ester; Prostaglandin F2α trimethylsilyl ether oxime derivative; PGF2α-TMS oxime ether; (13E,15S)-15-[(Trimethylsilyl)oxy]-9-[(ethoxyimino)]-5Z,13E-prostadien-1-oic acid trimethylsilyl ester; 15-TMS-PGF2α oxime ethyl ether TMS ester; 56009-45-1; Prosta-8(12),13-dien-1-oic acid, 9-(ethoxyimino)-15-(trimethylsiloxy)-, trimethylsilyl ester, (13E,15S)-
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Quality Control

Our production of (13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-8(12),13-Dien-1-Oic Acid Trimethylsilyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance Colorless to pale yellow viscous oil or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0% (Area %)
Related Substances (HPLC) Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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