Description

(5Z,13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-5,8(12),13-Trien-1-Oic Acid Trimethylsilyl Ester is a sophisticated synthetic prostaglandin derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its role as a protected, functionalized precursor for the synthesis of bioactive prostanoids and related therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on developing novel anti-inflammatory, cardiovascular, and ophthalmic drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prostaglandin analogs and other prostanoid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates targeting prostaglandin receptors.
• Biochemical Research: Serves as a tool compound for studying prostaglandin biosynthesis pathways and related enzymatic processes in vitro.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring protected carboxylic acid and hydroxyl functionalities.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Acts as a critical intermediate in scaling up the production of prostaglandin-derived therapeutics from laboratory to pilot and commercial scale.

Basic Information

Product Name	(5Z,13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-5,8(12),13-Trien-1-Oic Acid Trimethylsilyl Ester
CAS No.	56009-44-0
Molecular Formula	C29H51NO4Si2
Molecular Weight	533.90 g/mol
Synonyms	9-(Ethoxyimino)-15-(trimethylsiloxy)prosta-5,8(12),13-trien-1-oic acid trimethylsilyl ester; Prostaglandin F2α trimethylsilyl ether oxime derivative; TMS-PGF2α oxime ether; 15-Trimethylsiloxy-9-ethoxyiminoprosta-5,8(12),13-trien-1-oic acid TMS ester; (5Z,13E,15S)-15-[(Trimethylsilyl)oxy]-9-[(ethoxy)imino]prosta-5,8(12),13-trien-1-oic acid trimethylsilyl ester; PG Intermediate 56009-44-0
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-9-(Ethoxyimino)-15-(Trimethylsiloxy)Prosta-5,8(12),13-Trien-1-Oic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.