Description

Polyanetholesulfonic Acid Sodium is a synthetic, high-molecular-weight anionic polyelectrolyte known for its strong protein-binding and anticoagulant properties. This compound is essential for applications requiring the inhibition of blood coagulation and the stabilization of biological samples. It is a critical reagent for diagnostic laboratories, pharmaceutical research, and in vitro biological studies where precise control of the coagulation cascade is necessary.

Application

• Blood Collection Tubes: Used as a primary anticoagulant in vacuum blood collection systems (e.g., SPS tubes) for microbiological culture and molecular diagnostics.
• Diagnostic Reagents: A key component in in-vitro diagnostic (IVD) kits and reagents for hematology, serology, and immunoassay tests.
• Pharmaceutical Research: Employed in biochemical and pharmacological research to study blood clotting mechanisms, complement activation, and protein interactions.
• Cell Culture & Microbiology: Acts as an anticoagulant in media for the isolation and culture of fastidious microorganisms from blood samples.
• Molecular Biology: Utilized in DNA/RNA extraction protocols from whole blood to prevent clotting and inhibit nucleases.
• Biomaterial Coatings: Investigated for surface modifications to create non-thrombogenic coatings on medical devices.

Basic Information

Product Name	Polyanetholesulfonic Acid Sodium
CAS No.	55963-78-5
Molecular Formula	(C15H13NaO4S)n
Molecular Weight	~ 3,000 - 5,000 g/mol (Typical average)
Synonyms	Polyanethol Sulfonate Sodium Salt; Sodium Polyanetholesulfonate; SPS (Polyanetholesulfonic Acid Sodium); Liquoid; Poly(sodium 4-sulfonatooxybenzene); PAS-Na; 4-Hydroxybenzenesulfonic acid sodium salt polymer
EINECS	Contact for details

Quality Control

Our Polyanetholesulfonic Acid Sodium is manufactured under a strict quality management system. Each batch is tested to ensure it meets stringent specifications for identity, purity, and biological activity relevant to diagnostic and research applications. A comprehensive Certificate of Analysis (COA) detailing assay, viscosity, pH, and endotoxin levels is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (on dried basis)	≥ 95.0 %
pH (1% Solution)	6.0 - 8.0
Loss on Drying	≤ 5.0 %
Residue on Ignition (Sulfated Ash)	20.0 - 26.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Endotoxin	< 0.25 EU/mg (for diagnostic grades)
Biological Activity (Anticoagulant)	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.