Description

(7S,13E,16S,17E,20S)-7,20-Dihydroxy-10-(1H-Indol-3-Yl)-16,18-Dimethyl[13]Cytochalasa-5,13,17-Triene-1,19,23-Trione is a complex cytochalasan alkaloid, a class of fungal metabolites known for their potent bioactivity. This compound is a critical high-purity reference standard and research chemical for investigating cytoskeletal dynamics and cellular processes. It is primarily utilized by pharmaceutical R&D, academic research institutions, and biotechnology companies focused on drug discovery and cell biology.

Application

• Biochemical Research: As a reference standard in studies of actin polymerization and cytoskeleton disruption.
• Pharmaceutical Development: A key intermediate or lead compound in the discovery of novel therapeutics targeting cell motility and division.
• Cell Biology Studies: Used to investigate mechanisms of cytochalasin action, membrane trafficking, and endocytosis.
• Analytical Standard: For method development and quality control in HPLC, LC-MS, and NMR analysis within contract research organizations (CROs).
• Academic Research: Fundamental research into fungal metabolites and their structure-activity relationships (SAR).

Basic Information

Product Name	(7S,13E,16S,17E,20S)-7,20-Dihydroxy-10-(1H-Indol-3-Yl)-16,18-Dimethyl[13]Cytochalasa-5,13,17-Triene-1,19,23-Trione
CAS No.	55945-74-9
Molecular Formula	C₃₄H₃₉N₃O₆
Molecular Weight	577.70 g/mol
Synonyms	Cytochalasin Z8; Cytochalasin Z₈; [13]Cytochalasa-5,13,17-triene-1,19,23-trione, 7,20-dihydroxy-10-(1H-indol-3-yl)-16,18-dimethyl-, (7S,13E,16S,17E,20S)-; 7,20-Dihydroxy-10-(1H-indol-3-yl)-16,18-dimethyl[13]cytochalasa-5,13,17-triene-1,19,23-trione; NSC 339524
EINECS	Contact for details

Quality Control

Our high-purity research-grade cytochalasin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the exacting standards required for scientific research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.