Description

1,2-Bis(Bromomethyl)-4-Fluorobenzene is a versatile and highly reactive aromatic building block, primarily valued for its dual benzylic bromine functionalities. This compound is critical for facilitating efficient carbon-carbon bond formation and introducing fluorinated aromatic moieties into complex molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated aromatic structures for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed as a cross-linking agent or monomer to incorporate fluorine and bromine atoms into specialty polymers, improving flame retardancy and chemical resistance.
• Organic Synthesis Reagent: A valuable reagent in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions due to its reactive bromomethyl groups.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new fluorinated compounds and reaction methodologies.

Basic Information

Product Name	1,2-Bis(Bromomethyl)-4-Fluorobenzene
CAS No.	55831-04-4
Molecular Formula	C8H7Br2F
Molecular Weight	281.95 g/mol
Synonyms	4-Fluoro-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-4-fluorobenzene; α,α'-Dibromo-4-fluoro-o-xylene; 4-Fluoro-o-xylylene dibromide; 1,2-Di(bromomethyl)-4-fluorobenzene; 4-Fluoro-1,2-bis(bromomethyl)benzene; o-Xylylene-α,α'-dibromide, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Bromomethyl)-4-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.