Description

4-(1,1-Difluoroethyl)Benzaldehyde is a high-purity aromatic aldehyde building block featuring a difluoroethyl substituent. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, where its unique fluorine-containing moiety imparts desirable properties to target molecules. It is primarily sought by R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the difluoroethyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorine-containing compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Monomers: Employed in the creation of specialty polymers and coatings with tailored thermal, chemical, or surface properties.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the effects of fluorine substitution.
• Ligand & Catalyst Development: Used to synthesize novel chiral ligands and organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	4-(1,1-Difluoroethyl)Benzaldehyde
CAS No.	55805-22-6
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	p-(1,1-Difluoroethyl)benzaldehyde; 4-(1,1-Difluoroethyl)benzaldehyde; 1-[4-(Difluoromethyl)phenyl]ethanone (common misnomer); Benzaldehyde, 4-(1,1-difluoroethyl)-; α,α-Difluoro-4-acetyltoluene (related); 4-(Difluoroacetyl)benzaldehyde (precursor); 55805-22-6; p-Difluoroethylbenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(1,1-Difluoroethyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and highly volatile. Keep away from strong acids, organic solvents, heat, and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.