Description

1-Chloro-4-(1,1-Difluoroethyl)Benzene is a specialized fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chlorine and a difluoroethyl group on the benzene ring, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and process development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and stability.
• Organic Electronics: Employed in the synthesis of semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer backbones, enhancing chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	1-Chloro-4-(1,1-Difluoroethyl)Benzene
CAS No.	55805-04-4
Molecular Formula	C8H7ClF2
Molecular Weight	176.59 g/mol
Synonyms	p-(1,1-Difluoroethyl)chlorobenzene; 4-(1,1-Difluoroethyl)-1-chlorobenzene; 1-Chloro-4-(α,α-difluoroethyl)benzene; (4-Chlorophenyl)-1,1-difluoroethane; Benzene, 1-chloro-4-(1,1-difluoroethyl)-; 55805-04-4
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(1,1-Difluoroethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.