Description

(5Z,13E,15S)-15-Hydroxy-9-Oxoprosta-5,8(12),13-Trien-1-Oic Acid Methyl Ester is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and functional groups, which are critical for studying and modulating biological pathways related to inflammation, smooth muscle contraction, and cellular signaling. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on developing novel therapeutics and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of eicosanoid biology, receptor binding assays, and signal transduction pathways.
• Inflammation & Immunology Studies: Applied in preclinical research to investigate the role of prostaglandin metabolites in inflammatory responses and immune system modulation.
• Metabolite Standard: Employed in analytical laboratories as a certified reference material for the quantification of prostaglandin metabolites in biological samples via LC-MS or HPLC.
• Fine Chemical Synthesis: Acts as a versatile chiral synthon for the preparation of specialized compounds in medicinal chemistry and custom synthesis projects.

Basic Information

Product Name	(5Z,13E,15S)-15-Hydroxy-9-Oxoprosta-5,8(12),13-Trien-1-Oic Acid Methyl Ester
CAS No.	55760-05-9
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid methyl ester; 9-Oxo-15-hydroxy-5,8(12),13-prostatrienoic acid methyl ester; Methyl 15-hydroxy-9-oxoprosta-5,8(12),13-trien-1-oate; Prostaglandin A2 Methyl Ester; PGA2 Methyl Ester; 9-Keto-PGA2 Methyl Ester; 15-Hydroxy-9-ketoprosta-5,8(12),13-trien-1-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (5Z,13E,15S)-15-Hydroxy-9-Oxoprosta-5,8(12),13-Trien-1-Oic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and spectroscopic identification (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the container sealed in a dry, freezer environment. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.