Description

Cyclohexylpuromycin is a specialized puromycin derivative where the sugar moiety is modified with a cyclohexyl group. This structural alteration is significant for fine-tuning biological activity and physicochemical properties, making it a valuable research-grade biochemical. It is primarily utilized in life science research, particularly in studies of protein synthesis inhibition and ribosomal function. This compound serves as a critical tool for researchers in pharmacology, molecular biology, and biochemistry seeking to investigate and modulate specific cellular processes.

Application

• Biochemical Research: Used as a potent inhibitor of protein synthesis in eukaryotic cells for mechanistic studies.
• Antibiotic Mechanism Studies: Serves as a model compound to investigate the action of aminonucleoside antibiotics on ribosomes.
• Cell Line Selection: Employed in the development and maintenance of puromycin-resistant cell lines in genetic engineering workflows.
• Pharmacological Probes: Acts as a tool compound for studying translation termination and ribosomal peptidyl transferase activity.
• Veterinary Research: Potential use in research for antiprotozoal agents, given the activity profile of related puromycin derivatives.

Basic Information

Product Name	Cyclohexylpuromycin
CAS No.	55604-91-6
Molecular Formula	C23H30N6O5
Molecular Weight	470.52 g/mol
Synonyms	6-Dimethylamino-9-[3-deoxy-3-(cyclohexylamino)-β-D-ribofuranosyl]purine; Cyclohexylaminopuromycin; 3'-Cyclohexylaminopuromycin; 3'-Deoxy-3'-(cyclohexylamino)puromycin; N6,N6-Dimethyl-3'-deoxy-3'-(cyclohexylamino)adenosine; Cyclohexylpuromycin dihydrochloride (salt form); Puromycin, 3'-deoxy-3'-(cyclohexylamino)-
EINECS	Contact for details

Quality Control

Our Cyclohexylpuromycin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.