Description

p-Amidinophenyl p-(6-Amidino-2-Indolyl)Phenyl Ether Dihydrochloride is a high-purity, synthetic organic compound characterized by its amidine functional groups. This compound is valued for its role as a key intermediate and research chemical in advanced pharmaceutical and biochemical applications. It is primarily needed by R&D laboratories and manufacturers in the life sciences sector for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel protease inhibitors and other biologically active molecules.
• Biochemical Research: Used as a tool compound in enzymatic studies, particularly for investigating serine protease mechanisms and inhibition pathways.
• Diagnostic Reagent Development: Employed in the research and development of diagnostic assays and kits that target specific enzymatic activities.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies aimed at optimizing drug candidate potency and selectivity.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery projects.

Basic Information

Item	Details
Product Name	p-Amidinophenyl p-(6-Amidino-2-Indolyl)Phenyl Ether Dihydrochloride
CAS No.	55453-00-4
Molecular Formula	C21H19N5O · 2HCl
Molecular Weight	438.33 g/mol (Free base)
Synonyms	1,1'-[Oxybis(4,1-phenylene)]bis[1H-indole-6-carboximidamide] Dihydrochloride; APAIE Dihydrochloride; Bis-amidinodiphenyl Ether Derivative; 4,4'-Oxybis[N-(6-amidino-2-indolyl)benzamidine] Dihydrochloride; p-Amidinophenoxy-bis-indolecarboximidamide Dihydrochloride; Protease Inhibitor Intermediate; CAS 55453-00-4
EINECS	Contact for details

Quality Control

Our p-Amidinophenyl p-(6-Amidino-2-Indolyl)Phenyl Ether Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.