Description

Aflatoxicol H1 is a significant secondary metabolite and derivative of aflatoxin B1, a potent mycotoxin produced by certain Aspergillus species. This compound is of critical importance in toxicological research and analytical chemistry for studying the metabolic pathways, biological activity, and detoxification mechanisms of aflatoxins. It is primarily required by research institutions, diagnostic kit manufacturers, and quality control laboratories in the food safety, agricultural, and pharmaceutical sectors for use as a high-purity analytical reference standard.

Application

• Analytical Reference Standard: Serves as a critical certified reference material (CRM) for the precise calibration of analytical instrumentation such as HPLC, LC-MS/MS, and ELISA in mycotoxin testing laboratories.
• Toxicological Research: Used in biomedical and pharmacological studies to investigate the metabolism, bioactivation, carcinogenicity, and cellular effects of aflatoxin derivatives.
• Method Development & Validation: Essential for developing, optimizing, and validating new analytical methods for the detection and quantification of aflatoxins and their metabolites in complex matrices.
• Food & Feed Safety Testing: Employed in quality assurance/quality control (QA/QC) protocols to ensure the accuracy and reliability of test results for aflatoxin contamination in grains, nuts, spices, and animal feed.
• Diagnostic Reagent Manufacturing: Acts as a key antigen or hapten in the production of antibodies for immunoassay-based rapid test kits and biosensors.
• Regulatory Compliance & Proficiency Testing: Used by accreditation bodies and testing facilities to prepare samples for laboratory proficiency testing and to verify compliance with international regulatory limits (e.g., EU, FDA).

Basic Information

Item	Details
Product Name	Aflatoxicol H1
CAS No.	55446-27-0
Molecular Formula	C17H14O6
Molecular Weight	314.29 g/mol
Synonyms	Aflatoxicol H1; 2,3,6a,9a-Tetrahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; (6aR,9aR)-2,3,6a,9a-Tetrahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; Aflatoxin B1 metabolite; Aflatoxin B1 dihydrodiol derivative
EINECS	Contact for details

Quality Control

Every batch of Aflatoxicol H1 is manufactured and handled under strict quality management systems. The product undergoes rigorous identity confirmation, purity analysis, and stability testing to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from HPLC, NMR, and MS analyses to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.