Description

L-Lysine-13C6 is a stable isotope-labeled analog of the essential amino acid L-Lysine, where all six carbon atoms are the 13C isotope. This compound is critical for advanced research and analytical applications requiring precise metabolic tracing and quantification. It is primarily utilized by scientists and quality control professionals in the pharmaceutical, nutritional science, and biomedical research sectors for applications such as mass spectrometry-based proteomics, metabolic flux analysis, and the development of internal standards for accurate quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference in LC-MS and GC-MS analyses for accurate measurement of endogenous L-Lysine levels in complex biological matrices.
• Metabolic Pathway Tracing (Fluxomics): Used in 13C-isotope labeling studies to track and model metabolic fluxes in cells, tissues, or microorganisms.
• Proteomics Research: Incorporated into SILAC (Stable Isotope Labeling by Amino acids in Cell culture) workflows for comparative protein expression profiling.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace the metabolic fate of drug compounds containing lysine.
• Nutritional Science Research: Used to study protein metabolism, amino acid absorption, and utilization in humans and animals with high precision.
• Diagnostic Assay Development: Acts as a key component in calibrators and controls for clinical diagnostic tests measuring amino acid disorders.

Basic Information

Product Name	L-Lysine-13C6
CAS No.	55443-57-7
Molecular Formula	¹³C₆H₁₄N₂O₂
Molecular Weight	158.15 g/mol (for ¹³C₆)
Synonyms	(2S)-2,6-Diamino-¹³C₆-hexanoic acid; L-Lysine (U-¹³C₆); L-Lysine-13C6, 99 atom % 13C; L-2,6-Diaminocaproic acid-13C6; H-Lys-OH-13C6; (S)-2,6-Diamino-¹³C₆-hexanoic acid; Lysine-13C6; L-Lysine (13C6)
EINECS	Contact for details

Quality Control

Our L-Lysine-13C6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), chiral purity, and residual solvent content. We support compliance with relevant GMP guidelines for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.