Description

4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for introducing specific physicochemical properties into advanced molecular architectures. Its core value lies in the unique combination of the benzaldehyde moiety's reactivity with the lipophilicity and electron-withdrawing character imparted by the hexafluoropropoxy group. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly where enhanced membrane permeability and metabolic stability are required.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that benefit from the fluorine group's bioactivity and environmental persistence profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, improving device performance and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter surface energy, enhance chemical resistance, and improve optical properties.
• Cross-coupling Reactions: The aldehyde group is a versatile handle for further functionalization via reactions like Suzuki-Miyaura or reductive amination.
• Ligand & Catalyst Development: Used to prepare fluorinated ligands for catalysis, potentially influencing reaction selectivity and efficiency.

Basic Information

Product Name	4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzaldehyde
CAS No.	55321-69-2
Molecular Formula	C10H6F6O2
Molecular Weight	272.14 g/mol
Synonyms	p-(Hexafluoroisopropoxy)benzaldehyde; 4-(Hexafluoro-2-propanoxy)benzaldehyde; Benzaldehyde, 4-[(1,1,2,3,3,3-hexafluoropropoxy)]-; 4-(Perfluoroisopropoxy)benzaldehyde; 1,1,2,3,3,3-Hexafluoropropyl 4-formylphenyl ether; 4-[(1,1,2,3,3,3-Hexafluoropropoxy)]benzaldehyde; 4-(1,1,2,3,3,3-Hexafluoropropoxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.