Description

19-Hydroxyprostaglandin E1 is a key intermediate and metabolite in the prostaglandin biosynthetic pathway, offering significant value for research and pharmaceutical development. This compound is crucial for studying eicosanoid metabolism, cellular signaling, and the physiological roles of prostaglandin derivatives. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for use in analytical standards, biochemical research, and as a precursor for advanced therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and reagent in studies of prostaglandin biosynthesis, metabolism, and receptor interactions.
• Pharmaceutical Intermediates: Serves as a critical synthetic precursor or metabolite in the development of novel therapeutic agents targeting inflammation, cardiovascular function, and renal physiology.
• Analytical Standards: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for the quantification of prostaglandins and related eicosanoids in biological samples.
• Cell Signaling Studies: Applied in vitro to investigate the specific cellular pathways and physiological effects mediated by 19-hydroxy prostaglandin derivatives.
• Metabolite Identification: Used in drug metabolism and pharmacokinetics (DMPK) studies to identify and characterize the metabolic fate of prostaglandin-based drugs.

Basic Information

Product Name	19-Hydroxyprostaglandin E1
CAS No.	55123-67-6
Molecular Formula	C₂₀H₃₄O₆
Molecular Weight	370.48 g/mol
Synonyms	19-Hydroxy PGE1; 19(R)-Hydroxyprostaglandin E1; 19-OH-PGE1; (5Z,11α,13E,15S)-11,15,19-Trihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Prostaglandin E1 19-alcohol; 19-Hydroxy-(5Z,11α,13E,15S)-9-oxoprosta-5,13-dien-1-oic acid
EINECS	Contact for details

Quality Control

Our 19-Hydroxyprostaglandin E1 is produced and handled under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.