Description

15(R)-15-Methyl Prostaglandin E2 is a synthetic analog of prostaglandin E2, distinguished by a methyl group at the 15(R) position which enhances its metabolic stability and biological activity. This compound is a critical intermediate and research tool in the development of novel pharmaceuticals, particularly in the fields of reproductive health, gastroenterology, and inflammation. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis, and advanced life science research requiring high-purity bioactive lipid mediators.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and active agent in studies of prostaglandin receptors (EP receptors) and their signaling pathways.
• Reproductive Medicine Research: Investigated for applications related to cervical ripening, labor induction, and fertility treatments.
• Gastrointestinal Research: Employed in studies exploring cytoprotective effects on gastric mucosa and regulation of gastric acid secretion.
• Inflammation & Immunology Studies: Serves as a tool to modulate inflammatory responses and study immune cell function.
• Cell Culture & Toxicology: Used in specialized cell culture applications to study cellular responses and in toxicological assessments.

Basic Information

Product Name	15(R)-15-Methyl Prostaglandin E2
CAS No.	55028-70-1
Molecular Formula	C₂₂H₃₆O₅
Molecular Weight	380.52 g/mol
Synonyms	15(R)-15-Methyl PGE2; 15(R)-Methylprostaglandin E2; 11α,15R-Dihydroxy-15-methyl-9-oxoprosta-5Z,13E-dien-1-oic acid; Arbaprostil; 15-Methyl Prostaglandin E2 (15R-isomer); 15(R)-MePGE2; (±)-15-Methylprostaglandin E2 (related mixture)
EINECS	Contact for details

Quality Control

Our 15(R)-15-Methyl Prostaglandin E2 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.