Description

4-Pyridinol,2,3,5-Trifluoro-(9Ci) is a fluorinated pyridine derivative, a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring multiple fluorine atoms on the pyridine ring, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce fluorine atoms to modulate the biological activity, metabolic stability, and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers for electronic applications.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biomolecules for metabolic pathway studies and imaging.
• Custom Synthesis & Contract Manufacturing: A high-value building block for custom chemical synthesis services targeting fluorinated compound libraries.

Basic Information

Product Name	4-Pyridinol,2,3,5-Trifluoro-(9Ci)
CAS No.	54929-35-0
Molecular Formula	C5H2F3NO
Molecular Weight	149.07 g/mol
Synonyms	2,3,5-Trifluoropyridin-4-ol; 2,3,5-Trifluoro-4-hydroxypyridine; 4-Hydroxy-2,3,5-trifluoropyridine; 2,3,5-Trifluoro-4-pyridinol; 4-Pyridinol, 2,3,5-trifluoro- (9CI)
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 4-Pyridinol,2,3,5-Trifluoro-(9Ci) typically meets a purity specification of ≥97% (by HPLC), with options for higher grades (≥98%, ≥99%) available. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.