Description

Clindamycin B 2-Phosphate is a key phosphate ester derivative of the lincosamide antibiotic, Clindamycin B. This compound serves as a critical pharmaceutical intermediate in the synthesis of more soluble and bioavailable clindamycin prodrugs and formulations. It is essential for manufacturers in the pharmaceutical industry, particularly those developing injectable antibiotic solutions and topical preparations where enhanced solubility and stability are required.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of clindamycin phosphate, a widely used antibiotic prodrug.
• Injectable Antibiotic Formulations: A key precursor for creating sterile, water-soluble injectable solutions for systemic bacterial infections.
• Topical Gel and Lotion Production: Used in the manufacture of topical formulations for treating acne and other skin infections.
• Veterinary Medicine: Employed in the development of antibiotic treatments for bacterial infections in animals.
• Research & Development: Serves as a standard and building block in microbiological and pharmacological research for novel antibiotic derivatives.
• GMP Manufacturing: Supplied as a raw material for Good Manufacturing Practice (GMP) production of finished dosage forms.

Basic Information

Product Name	Clindamycin B 2-Phosphate
CAS No.	54887-31-9
Molecular Formula	C18H34ClN2O8PS
Molecular Weight	504.94 g/mol
Synonyms	Clindamycin B Dihydrogen Phosphate; 7(S)-Chloro-7-deoxylincomycin 2-phosphate; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(phosphonooxy)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide; Lincomycin B, 2-(dihydrogen phosphate), 7-chloro-7-deoxy-; U-28508; Antibiotic U 28508
EINECS	Contact for details

Quality Control

Our Clindamycin B 2-Phosphate is produced and tested under a strict quality management system. We ensure compliance with relevant pharmaceutical standards, and the product is typically characterized to meet high-purity specifications suitable for GMP manufacturing. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.