Description

Clindamycin 4-Phosphate is a water-soluble phosphate ester derivative of the lincosamide antibiotic clindamycin. This chemical modification is critical for enhancing the stability and bioavailability of the parent compound, making it suitable for injectable pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of sterile injectable antibiotics. The compound offers a reliable solution for formulating stable, parenteral dosage forms targeting anaerobic and Gram-positive aerobic bacterial infections.

Application

• Active Pharmaceutical Ingredient (API) for sterile injectable antibiotic formulations.
• Pharmaceutical Intermediate in the synthesis of clindamycin-based parenteral drugs.
• Research and development of novel antibiotic delivery systems and prodrugs.
• Manufacturing of hospital-use injectables for serious skin, soft tissue, and intra-abdominal infections.
• Quality control and analytical reference standard in pharmaceutical laboratories.
• Component in combination therapies for surgical prophylaxis.

Basic Information

Item	Details
Product Name	Clindamycin 4-Phosphate
CAS No.	54887-30-8
Molecular Formula	C18H34ClN2O8PS
Molecular Weight	504.94 g/mol
Synonyms	Clindamycin 4-Dihydrogen Phosphate; Clindamycin Phosphate (USP); 7(S)-Chloro-7-deoxylincomycin 4-phosphate; U-28508; Dalacin® Phosphate; Cleocin Phosphate; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide 4-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our Clindamycin 4-Phosphate is manufactured and tested to meet stringent pharmaceutical-grade standards, including relevant monographs from the United States Pharmacopeia (USP) and European Pharmacopoeia (Ph. Eur.). Each batch undergoes comprehensive analytical testing for identity, purity, potency, and specified impurities. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Bacterial Endotoxins	< 0.6 EU/mg (for injectable grade)
Sterility (where applicable)	Sterile (for sterile-finished API grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.