Description

Siastatin B is a potent and specific inhibitor of α-glucosidase enzymes, which are critical for carbohydrate digestion. This compound is a valuable biochemical tool for metabolic research and a key intermediate in the development of therapeutic agents targeting diabetes and related metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemical reagents.

Application

• Biochemical Research: As a specific α-glucosidase inhibitor for studying carbohydrate metabolism, enzyme kinetics, and inhibition mechanisms.
• Pharmaceutical Development: Serves as a critical reference standard and intermediate in the discovery and synthesis of novel anti-diabetic drugs.
• Diagnostic Reagent Manufacturing: Used in the formulation of enzyme assay kits for clinical and research laboratories to measure α-glucosidase activity.
• Metabolic Pathway Analysis: A tool for probing and validating metabolic pathways in cell-based and in-vivo studies related to sugar absorption.
• Academic & Industrial R&D: Essential for high-throughput screening (HTS) campaigns to identify new therapeutic candidates for metabolic diseases.

Basic Information

Product Name	Siastatin B
CAS No.	54795-58-3
Molecular Formula	C7H14N2O4
Molecular Weight	190.20 g/mol
Synonyms	Siastatin B; (2R,3R,4R,5S)-1,2-Bis(hydroxymethyl)-3,4,5-piperidinetriol; 1,2-Dideoxy-1,2-imino-D-mannitol; DIM (1,2-Dideoxy-1,2-imino-D-mannitol); α-Glucosidase Inhibitor Siastatin B; 1,2-Dideoxynojirimycin derivative; Deoxymannojirimycin isomer
EINECS	Contact for details

Quality Control

Our Siastatin B is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for laboratory and research-grade chemicals to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.