Description

Pentazocine Glucuronide is a major, pharmacologically relevant metabolite of the analgesic drug pentazocine. This compound is of critical importance for pharmaceutical research and development, particularly in the fields of drug metabolism, pharmacokinetic studies, and forensic toxicology. It serves as a vital reference standard for analytical laboratories, enabling accurate quantification and identification of pentazocine and its metabolites in biological matrices.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for calibrating analytical instruments and validating methods in drug testing.
• Metabolite Research: Essential for studying the metabolic pathways, bioavailability, and clearance rates of pentazocine in preclinical and clinical research.
• Forensic & Clinical Toxicology: Used to develop and confirm assays for detecting pentazocine abuse or monitoring therapeutic drug levels in blood, urine, or plasma samples.
• Bioanalytical Method Development: A key component in establishing robust HPLC, LC-MS/MS, or GC-MS protocols for metabolite profiling.
• Quality Control in Manufacturing: Employed to ensure the consistency and purity of pentazocine-based pharmaceutical products during production.
• Regulatory Compliance & Doping Control: Supports laboratories in meeting stringent regulatory requirements for substance identification in sports anti-doping and workplace testing programs.

Basic Information

Product Name	Pentazocine Glucuronide
CAS No.	54763-91-6
Molecular Formula	C28H36N2O8
Molecular Weight	528.60 g/mol
Synonyms	Pentazocine Glucuronide; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol Glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[[(1R,5R,9R)-5,9-dimethyl-2-(3-methylbut-2-enyl)-2-azabicyclo[3.3.1]nonan-9-yl]oxy]oxane-2-carboxylic acid; Pentazocine O-Glucuronide; Win 20,228 Glucuronide
EINECS	Contact for details

Quality Control

Our Pentazocine Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and reference applications. A detailed Certificate of Analysis (COA) containing batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.