Description

Fumaric Acid-2 3-14C CAS NO 54744-93-3 is a carbon-14 labeled isotopologue of fumaric acid, a key intermediate in the citric acid cycle. This radiolabeled compound is essential for advanced metabolic and pharmacokinetic studies, providing critical tracer capabilities. It is primarily utilized by research scientists and pharmaceutical developers in the fields of biochemistry, drug metabolism, and life science research.

Application

• Tracer Studies in Biochemistry: Used to elucidate metabolic pathways, including the Krebs cycle, in both in vitro and in vivo systems.
• Drug Metabolism and Pharmacokinetics (DMPK): A vital tool for tracking the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities in preclinical research.
• Mechanistic Research: Enables detailed investigation into enzyme mechanisms and substrate utilization within cellular respiration.
• Agricultural Chemistry Research: Applied in studies of plant metabolism and the environmental fate of agrochemicals.
• Quality Control Reference Standard: Serves as an authenticated standard in analytical method development and validation for related compounds.

Basic Information

Item	Details
Product Name	Fumaric Acid-2 3-14C
CAS No.	54744-93-3
Molecular Formula	C4H414C2O4 or C4H4O4 (with 14C at positions 2 & 3)
Molecular Weight	~118.06 g/mol (exact mass depends on specific activity)
Synonyms	(2,3-14C)Fumaric Acid; Fumaric-2,3-14C Acid; (E)-Butenedioic-2,3-14C Acid; Allomaleic-2,3-14C Acid; Boletic-2,3-14C Acid; Trans-1,2-Ethylenedicarboxylic-2,3-14C Acid; Lichenic-2,3-14C Acid; 14C-Labeled Fumaric Acid
EINECS	Contact for details

Quality Control

Every batch of our Fumaric Acid-2 3-14C is produced and analyzed under strict quality protocols to ensure high chemical and radiochemical purity. Our quality commitment includes verification of specific activity and confirmation of isotopic labeling position. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and analytical methods (HPLC, NMR, MS) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures of 2-8°C or as specified on the label. This product should be handled in accordance with all local regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solvent (if supplied as solution)	Specified on label

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.