Description

4-Bromo-3-Chloro-2,5,6-Trifluoropyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring bromine, chlorine, and fluorine substituents, makes it an indispensable intermediate for introducing specific halogen patterns into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen pattern influences bioactivity and stability.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, functionalized polymers, or liquid crystal materials.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig couplings to form complex biaryl structures.
• Fluorinated Building Block: Provides a source of fluorine atoms for designing molecules with improved metabolic stability, lipophilicity, and membrane permeability.

Basic Information

Product Name	4-Bromo-3-Chloro-2,5,6-Trifluoropyridine
CAS No.	54732-63-7
Molecular Formula	C5BrClF3N
Molecular Weight	248.41 g/mol
Synonyms	2,5,6-Trifluoro-4-bromo-3-chloropyridine; 3-Chloro-4-bromo-2,5,6-trifluoropyridine; 4-Bromo-3-chloro-2,5,6-trifluoropyridine; Pyridine, 4-bromo-3-chloro-2,5,6-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-2,5,6-Trifluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound should be handled in accordance with good laboratory practices, using appropriate personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.