Description

17α-Acetyloxy-19,20-Didehydroyohimban-16α-Carboxylic Acid Methyl Ester is a key synthetic intermediate in the production of complex indole alkaloids and pharmaceutical compounds. Its value lies in its specific stereochemistry and functional groups, which are critical for constructing molecules with targeted biological activity. This high-purity intermediate is essential for research and development laboratories and manufacturers in the pharmaceutical and fine chemical sectors, particularly those focused on central nervous system (CNS) agents and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those derived from yohimbane alkaloids.
• Research & Development: Used in medicinal chemistry for the discovery and development of new drug candidates targeting neurological and cardiovascular pathways.
• Fine Chemical Synthesis: Serves as a specialized precursor for synthesizing complex natural product analogs and other high-value organic compounds.
• Reference Standard: Can be utilized as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	17α-Acetyloxy-19,20-Didehydroyohimban-16α-Carboxylic Acid Methyl Ester
CAS No.	54725-62-1
Molecular Formula	C23H26N2O4
Molecular Weight	394.47 g/mol
Synonyms	Methyl 17α-acetoxy-19,20-didehydroyohimban-16α-carboxylate; 16α-Carbomethoxy-17α-acetoxy-19,20-didehydroyohimban; Methyl (16α,17α)-17-(acetyloxy)-19,20-didehydroyohimban-16-carboxylate; 17α-Acetoxy-19,20-didehydroyohimban-16α-carboxylic acid methyl ester; Ajmalicine derivative intermediate; Yohimban-16α-carboxylic acid, 17-(acetyloxy)-19,20-didehydro-, methyl ester, (16α,17α)-
EINECS	Contact for details

Quality Control

Our 17α-Acetyloxy-19,20-Didehydroyohimban-16α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.