Description

2-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical building block characterized by its reactive sulfonyl chloride group and halogenated aromatic ring. This compound matters for its critical role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), enabling the introduction of sulfonamide and other functional groups. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and functional materials with unique surface properties.
• Chemical Research & Development: Employed in organic synthesis for C-S bond formation and as a versatile electrophile in nucleophilic substitution reactions.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing advanced colorants and photographic chemicals.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	54403-98-4
Molecular Formula	C7H3BrClF3O2S
Molecular Weight	323.51 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-toluenesulfonyl chloride; 4-(Trifluoromethyl)-2-bromobenzenesulfonyl chloride; 2-Bromo-4-trifluoromethylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-4-(trifluoromethyl)-; p-Toluenesulfonyl chloride, 2-bromo-α,α,α-trifluoro-; 2-Bromo-α,α,α-trifluoro-4-methylbenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.