Description

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 6 is a high-purity biochemical reagent critical for advanced life science research and pharmaceutical development. This compound serves as a key tool for investigating complex intracellular signaling pathways, particularly those involving the MAPK cascade, which regulates essential cellular processes. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in signal transduction studies, drug discovery, and the development of targeted therapeutics for conditions like cancer and inflammatory diseases.

Application

• Biochemical Research: A fundamental reagent for studying the structure, function, and regulation of the MAPKKKK family in cellular signaling cascades.
• Drug Discovery & Screening: Used as a target or reference standard in high-throughput screening (HTS) assays to identify novel kinase inhibitors or modulators.
• Enzymology Studies: Essential for kinetic analysis, substrate specificity determination, and mechanistic studies of kinase activity.
• Cell Signaling Pathway Analysis: Employed in in vitro and cell-based assays to elucidate the role of MAP3K4 in stress response, differentiation, and apoptosis.
• Pharmaceutical Development: Acts as a critical reference standard for quality control and assay validation during the development of kinase-targeted drugs.
• Academic Research: Supports fundamental research in molecular biology, cancer biology, and immunology within university and institutional labs.

Basic Information

Product Name	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 6
CAS No.	54391-82-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MAP3K4; MEKK4; MAPK/ERK Kinase Kinase 4; MEK Kinase 4; Mitogen-Activated Protein Kinase Kinase Kinase 4; MAPKKK4; Protein Kinase, Lysine-Deficient 1; KIAA0213; EC 2.7.11.25
EINECS	Contact for details

Quality Control

Our Mitogen-Activated Protein Kinase Kinase Kinase Kinase 6 is produced under stringent quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, activity, and identity verification. We adhere to relevant industry standards for research-grade biochemicals to support your critical work in drug discovery and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Biological Activity	Assayed; data on COA
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO or specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.