Description

4'',5''-Bisnor-Delta(1)-Tetrahydrocannabinol-7,3''-Dicarboxylic Acid is a key cannabinoid-derived synthetic intermediate and reference standard of significant interest in pharmaceutical research and analytical chemistry. This compound matters for its role as a precursor and a critical marker in the synthesis and quality control of more complex cannabinoid-based active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical development laboratories, and manufacturers specializing in the production of high-purity cannabinoid derivatives for therapeutic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, purity assessment, and quantification of cannabinoid derivatives in analytical methods like HPLC and LC-MS.
• Synthetic Intermediate: Serves as a crucial building block in the multi-step organic synthesis of novel tetrahydrocannabinol (THC) analogs and other cannabinoid compounds for medicinal research.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to study the breakdown and effects of cannabinoids within biological systems.
• Impurity Profiling: Acts as a known impurity standard in the quality control of bulk cannabinoid APIs to ensure product safety and regulatory compliance.
• Forensic Analysis: Utilized as an analytical standard in forensic laboratories for the precise identification and differentiation of synthetic cannabinoids.

Basic Information

Product Name	4'',5''-Bisnor-Delta(1)-Tetrahydrocannabinol-7,3''-Dicarboxylic Acid
CAS No.	54388-16-8
Molecular Formula	C20H24O6
Molecular Weight	360.40 g/mol
Synonyms	4'',5''-Bisnor-δ1-THC-7,3''-dicarboxylic acid; 7,3''-Dicarboxy-4'',5''-bisnor-δ1-tetrahydrocannabinol; δ1-THC-7,3''-dicarboxylic acid bisnor homologue; Cannabinoid dicarboxylic acid intermediate; THC metabolite analog; 1,2-Dihydroxy-3-pentyl-9,10-dihydro-6H-dibenzo[b,d]pyran-7,8-dicarboxylic acid (related IUPAC-style name).
EINECS	Contact for details

Quality Control

Our 4'',5''-Bisnor-Delta(1)-Tetrahydrocannabinol-7,3''-Dicarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.