Description

(+)-Fluprostenol CAS NO 54276-17-4 is a synthetic prostaglandin analog, specifically a potent and selective agonist for the FP prostanoid receptor. This compound is of significant value in biomedical research and pharmaceutical development due to its high biological activity and structural specificity. It is primarily required by research institutions and pharmaceutical companies engaged in ophthalmology, reproductive biology, and the study of smooth muscle physiology.

Application

• Ophthalmology Research: Used as a key tool compound to study intraocular pressure (IOP) dynamics and to model conditions like glaucoma for the development of novel therapeutics.
• Pharmaceutical Intermediate: Serves as a critical building block or reference standard in the synthesis and quality control of advanced prostaglandin-based pharmaceutical agents.
• Cell Signaling Studies: Employed in vitro to investigate FP receptor-mediated signaling pathways, calcium mobilization, and cellular responses in relevant tissue models.
• Veterinary & Animal Science: Applied in reproductive studies for its luteolytic properties and in research concerning parturition induction in certain animal models.
• Smooth Muscle Pharmacology: Utilized to study the contraction and relaxation mechanisms of vascular, uterine, and other smooth muscle tissues.

Basic Information

Product Name	(+)-Fluprostenol
CAS No.	54276-17-4
Molecular Formula	C₂₃H₂₉FO₆
Molecular Weight	420.47 g/mol
Synonyms	Fluprostenol; 7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-5-heptenoic acid, 9,11,15-trihydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranor-; 16-(3-Trifluoromethylphenoxy)tetranor PGF2α; 9α,11α,15α-Trihydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid; Travoprost related compound; AL-5848; (+)-9,11,15-Trihydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranorprosta-4,5,13-trien-1-oic acid
EINECS	Contact for details

Quality Control

Our (+)-Fluprostenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.