Description

15(R)-19(R)-Hydroxy Prostaglandin E2 is a specialized, biologically active prostaglandin analog, a key intermediate in the synthesis of advanced pharmaceutical compounds and biochemical research tools. Its value lies in its high stereochemical purity and defined structure, which are critical for ensuring consistent biological activity and reliable research outcomes in sensitive applications. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutics, particularly in the fields of ophthalmology, dermatology, and inflammation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced prostaglandin-based drugs, including those for glaucoma treatment and ulcer therapy.
• Biochemical Research: Used as a high-purity reference standard and active agent in studies of prostaglandin receptors, signal transduction pathways, and cellular inflammation mechanisms.
• Cell Culture & In Vitro Studies: Employed to investigate the effects of specific prostaglandin metabolites on cell proliferation, differentiation, and apoptosis in controlled laboratory settings.
• Fine Chemical Synthesis: Serves as a chiral starting material or intermediate for the custom synthesis of complex, stereospecific molecules for clinical and pre-clinical development.
• Metabolite Standard: Utilized in analytical laboratories (LC-MS, HPLC) as a certified reference material for the quantification of prostaglandin pathways in biological samples.

Basic Information

Product Name	15(R)-19(R)-Hydroxy Prostaglandin E2
CAS No.	54142-29-9
Molecular Formula	C₂₀H₃₄O₆
Molecular Weight	370.48 g/mol
Synonyms	15(R)-19(R)-Dihydroxy Prostaglandin E2; 15(R),19(R)-DH-PGE2; (5Z,13E)-(9S,11R,15R,19R)-9,11,15,19-Tetrahydroxyprosta-5,13-dien-1-oic Acid; 15(R),19(R)-Dihydroxy-PGE2; 15(R),19(R)-DiH-PGE2; PGE2 metabolite; 15,19-Dihydroxyprostaglandin E2 (15R,19R-isomer)
EINECS	Contact for details

Quality Control

Every batch of 15(R)-19(R)-Hydroxy Prostaglandin E2 is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area designated for laboratory chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.