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n-Ethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide CAS NO 54130-36-8


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CAS No.:54130-36-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Ethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide is a high-purity synthetic prostaglandin derivative, specifically an ethylamide analog of a key trihydroxy prostanoid. This compound is of significant interest for advanced pharmaceutical research and development due to its potential as a potent and selective ligand for prostaglandin receptors. It is primarily utilized by pharmaceutical R&D laboratories and biochemical research institutions for developing novel therapeutic agents and conducting critical pharmacological studies.

Application

  • Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel prostaglandin-based therapeutics targeting inflammation, pain, and cardiovascular functions.
  • Biochemical Assay Development: For use as a high-purity ligand in receptor binding studies, enzyme inhibition assays, and signal transduction pathway analysis.
  • Reference Standard Manufacturing: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
  • Academic & Institutional Research: Used in university and government labs for fundamental studies on eicosanoid biology, lipid mediator pathways, and drug discovery.
  • Preclinical Studies: Employed in animal model research to investigate the pharmacokinetics, pharmacodynamics, and efficacy of prostaglandin analogs.

Basic Information

Product Name n-Ethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide
CAS No. 54130-36-8
Molecular Formula C22H37NO4
Molecular Weight 379.54 g/mol
Synonyms 9α,11α,15S-Trihydroxyprosta-5Z,13E-dien-1-oic Acid, N-Ethylamide; 9α,11α,15-Trihydroxyprosta-5Z,13E-dien-1-oic Acid Ethylamide; Prostaglandin Ethylamide Derivative; n-Ethyl Prostanoid Amide; 9,11,15-Trihydroxyprostadienoic Acid Ethylamide; PGE2 Ethylamide Analog; (5Z,13E,9α,11α,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid N-Ethylamide
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Quality Control

Our n-Ethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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