Description

2-(Trifluoromethyl)Phenacyl Bromide is a versatile and highly reactive organic bromide intermediate, characterized by the presence of a phenacyl bromide moiety and a trifluoromethyl group. This combination makes it a valuable building block for introducing the trifluoromethylphenyl motif into more complex molecules, a key strategy in modern pharmaceutical and agrochemical design. It is primarily sought after by research chemists and process development scientists in the fine chemical and life science industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and functional molecules for specialty polymers and advanced materials.
• Fluorine Chemistry Building Block: Essential for introducing the CF3 group into complex aromatic systems in medicinal and synthetic chemistry.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	2-(Trifluoromethyl)Phenacyl Bromide
CAS No.	54109-16-9
Molecular Formula	C9H6BrF3O
Molecular Weight	267.04 g/mol
Synonyms	2-Bromo-1-[2-(trifluoromethyl)phenyl]ethanone; α-Bromo-2'-(trifluoromethyl)acetophenone; 2'-(Trifluoromethyl)phenacyl bromide; 1-(2-Trifluoromethylphenyl)-2-bromoethanone; 2-Bromo-2'-(trifluoromethyl)acetophenone; ω-Bromo-2'-trifluoromethylacetophenone; (2-Trifluoromethylphenyl)bromomethyl ketone
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Phenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.