Description

2-Chloro-5-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated aromatic structure. This compound is essential for introducing the 2-chloro-5-(trifluoromethyl)benzenesulfonyl moiety into target molecules, enabling the synthesis of advanced materials and active ingredients. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs), including potential candidates for enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and sulfonyl groups contribute to biological activity and environmental stability.
• Dyestuff and Pigment Manufacturing: Serves as a precursor for creating specialized sulfonated dyes and pigments with unique color fastness and solubility properties.
• Polymer Modification: Employed to introduce functional sulfonyl chloride groups into polymer chains for creating ion-exchange resins or specialty polymers with tailored surface characteristics.
• Organic Synthesis Reagent: A versatile reagent in research laboratories for constructing complex organic molecules, particularly in nucleophilic substitution reactions to form sulfonamides, sulfonate esters, and sulfonic acids.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	54090-08-3
Molecular Formula	C7H3Cl2F3O2S
Molecular Weight	278.06 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-p-toluenesulfonyl chloride; 2-Chloro-α,α,α-trifluoro-p-toluenesulphonyl chloride; 4-Chloro-α,α,α-trifluoro-m-toluenesulfonyl chloride; 2-Chloro-5-(trifluoromethyl)benzene-1-sulfonyl chloride; 4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride; 2-Chloro-α,α,α-trifluoro-4-methylbenzenesulfonyl chloride; 2-Chloro-5-(trifluoromethyl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.