Description

Leurosine Sulfate is a sulfate salt derivative of the naturally occurring Vinca alkaloid, leurosine. This compound is of significant interest in pharmaceutical research and development due to its structural relationship to bioactive molecules. It serves as a critical intermediate or reference standard for scientists in oncology and medicinal chemistry. Key industries requiring this material include pharmaceutical R&D, biotechnology, and fine chemical synthesis.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods for quality control of active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Acts as a key intermediate or precursor in the synthesis and structure-activity relationship (SAR) studies of novel therapeutic agents.
• Oncology R&D: Employed in biological screening and assay development to investigate mechanisms related to its parent compound's activity.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies of plant alkaloids.
• Analytical Method Development: Serves as a known compound for developing and validating chromatographic (e.g., HPLC, LC-MS) and spectroscopic methods.

Basic Information

Product Name	Leurosine Sulfate
CAS No.	54081-68-4
Molecular Formula	C46H58N4O10 • H2SO4
Molecular Weight	~ 915.0 g/mol (for the sulfate salt)
Synonyms	Leurosine sulfate salt; Vincaleukoblastine, sulfate (1:1); 3',4'-Didehydro-4'-deoxyvincaleukoblastine sulfate; NSC 38297 sulfate; Vincoleurosine sulfate; Leurosine hydrogen sulfate
EINECS	Contact for details

Quality Control

Our Leurosine Sulfate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods and purity assessment by HPLC, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.