Description

Lodoxamide is a potent and selective mast cell stabilizer, primarily recognized for its therapeutic action in managing allergic conditions. This compound is of significant commercial interest due to its high specificity and established efficacy in pharmaceutical formulations. It is a critical active pharmaceutical ingredient (API) for manufacturers in the ophthalmic and respiratory drug sectors, serving global markets that demand reliable, high-purity chemical intermediates.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in ophthalmic solutions for allergic conjunctivitis.
• Key component in the research and development of mast cell stabilizer drugs.
• Used in the synthesis of advanced pharmaceutical intermediates targeting allergic and inflammatory pathways.
• Reference standard in analytical laboratories for quality control and method validation (HPLC, GC).
• Starting material for preclinical and clinical studies in immunology and allergy research.
• Potential applications in veterinary pharmaceuticals for managing allergic responses in animals.

Basic Information

Product Name	Lodoxamide
CAS No.	53882-12-5
Molecular Formula	C11H6ClN2O5
Molecular Weight	281.63 g/mol
Synonyms	Lodoxamide Tromethamine (USAN); U-42585; Lodoxamide Trometamol; 2,2'-[1,2-Ethanediylbis(imino-2,1-ethanediyloxy-2,1-phenylene)]bis(4-oxo-4H-1-benzopyran-8-carboxylic acid); Alomide (brand name); Oxamide, N,N'-bis(2-carboxy-4-oxo-6-chromanyl)ethylenedi-; Lodoxamidum [Latin]; Lodoxamid
EINECS	Contact for details

Quality Control

Our Lodoxamide is manufactured under strict quality management systems to ensure it meets the stringent requirements of the pharmaceutical industry. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, to guarantee consistency and reliability. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.