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Octakis-6-Bromo-6-Deoxy-γ-Cyclodextrin CAS NO 53784-84-2


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CAS No.:53784-84-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Octakis-6-Bromo-6-Deoxy-γ-Cyclodextrin is a chemically modified derivative of γ-cyclodextrin, where all eight primary hydroxyl groups are substituted with bromine atoms. This halogenation significantly alters the host-guest interaction properties, making it a powerful tool for molecular encapsulation and complexation studies. It is primarily utilized by researchers and formulators in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel delivery systems, chiral separations, and as a synthetic intermediate for further functionalization.

Application

  • Pharmaceutical Research & Development: As a host molecule for solubility enhancement, stabilization of active pharmaceutical ingredients (APIs), and controlled release studies.
  • Chiral Separation Science: Serving as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for enantiomer resolution.
  • Chemical Synthesis: Acting as a versatile synthetic intermediate for the preparation of other selectively functionalized cyclodextrin derivatives via nucleophilic substitution reactions.
  • Material Science: Used in the fabrication of functional polymers, sensors, and nano-assemblies due to its modified cavity and reactivity.
  • Agrochemical Formulations: Potential application in enhancing the delivery and bioavailability of agrochemicals.
  • Catalysis: As a building block for constructing supramolecular catalysts with unique microenvironments.

Basic Information

Product Name Octakis-6-Bromo-6-Deoxy-γ-Cyclodextrin
CAS No. 53784-84-2
Molecular Formula C~48~H~72~Br~8~O~32~
Molecular Weight ~2000.6 g/mol
Synonyms Per-6-Bromo-γ-cyclodextrin; γ-Cyclodextrin, octakis(6-bromo-6-deoxy)-; Octakis(6-bromo-6-deoxy)-γ-cyclodextrin; 6-Bromo-6-deoxy-γ-cyclodextrin, octakis-; Brominated Gamma Cyclodextrin; γ-CD-Br8; 6^I-VIII-Bromo-6^I-VIII-deoxy-γ-cyclodextrin
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Quality Control

Our Octakis-6-Bromo-6-Deoxy-γ-Cyclodextrin is produced under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency. Standard analytical techniques including HPLC, NMR, and Mass Spectrometry are employed. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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